GPCR Internalization and Trafficking

GPCR Internalization and Trafficking Assays

GPCRs are an important class of proteins for therapeutic development. Spectra has a full line of tagged GPCRs and validated cell lines for GPCR Internalization, trafficking and screening. Homogeneous assays utilizing Fluorogen Activating Peptide (FAP) technology have proven to...

Fluorogen Activating Protein (FAP) Technology

Fluorogen activating protein – FAP-tags® are a new class of small genetically encoded reporters that exhibit fluorescence only in the presence of micromolar concentrations of particular nontoxic soluble fluorogens. FAP-tags® allow the user to turn the fluorescent signal...

Validated Cell Lines for GPCR Internalization

SpectraGenetics has validated more than 30 cell lines expressing FAP-tagged GPCRs accross 3 assay formats; 1-color internalization, 2-color internalization and 2-color/2 target Multi-plex. 2-Color Pulse/Chase Internalization and Trafficking (Original Publication): ADRB2 ...

Services

Our skilled molecular biologists provide expertise and innovation in designing and constructing new FAP-tagged GPCRs and creating and validating stable cell lines expressing these tagged GPCRs.

Fluorogen Activating Protein (FAP) Technology

GPCR Internalization and Trafficking Assays

GPCRs are an important class of proteins for therapeutic development. Spectra has a full line of tagged GPCRs and validated cell lines for GPCR Internalization, trafficking and screening.

GPCR Fluorogen Exchange Assays

GPCRs are an important class of proteins for therapeutic development. Spectra has a full line of tagged GPCRs and validated cell lines for GPCR Internalization, trafficking and screening.