GPCR Internalization and Trafficking Assays
GPCRs are an important class of proteins for therapeutic development. Spectra has a full line of tagged GPCRs and validated cell lines for GPCR Internalization, trafficking and screening. Homogeneous assays utilizing Fluorogen Activating Peptide (FAP) technology have proven to...
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Fluorogen Activating Peptide (FAP) Technology
Fluorogen activating peptide – FAP-tags® are a new class of small genetically encoded reporters that exhibit fluorescence only in the presence of micromolar concentrations of particular nontoxic soluble fluorogens. FAP-tags® allow the user to turn the fluorescent...
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Validated Cell Lines for GPCR Internalization
SpectraGenetics has validated more than 30 cell lines expressing FAP-tagged GPCRs accross 3 assay formats; 1-color internalization, 2-color internalization and 2-color/2 target Multi-plex. 2-Color Pulse/Chase Internalization and Trafficking (Original Publication): ADRB2 ...
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Fluorogen Activating Peptide (FAP) Technology
Fluorogen activating peptide – FAP-tags® are a new class of small genetically encoded reporters that exhibit fluorescence only in the presence of micromolar concentrations of particular nontoxic soluble fluorogens.
GPCR Internalization and Trafficking Assays
GPCRs are an important class of proteins for therapeutic development. Spectra has a full line of tagged GPCRs and validated cell lines for GPCR Internalization, trafficking and screening.
GPCR Fluorogen Exchange Assays
GPCRs are an important class of proteins for therapeutic development. Spectra has a full line of tagged GPCRs and validated cell lines for GPCR Internalization, trafficking and screening.