GFP-tagged Mouse Embryonic Stem Cell Lines
...ll of a particular clonal line will serve as a reporter for the expression level and subcellular localization of the tagged protein in that cell line. Since these cells are embryonic stem cells they can be manipulated in culture into specific tissue-types such as cardiomyocytes, to create a powerful new system for biomarker discovery and drug-screening relevant to important diseases such as cardiovascular disease. Further, these mES cells can also...
Read MoreCustom Gene Tagging and Generation of Stable Cell lines
...over commonly used cDNA constructs: Tagged proteins are produced at native levels. The full repertoire of splice-isoforms is produced. Tagged proteins exhibit native subcellular localization and native biological function SpectraGenetics can also generate stable cell lines expressing any of our full length genes. To discuss the construction of a new gene, tagging vector or cell line, please send an email to techsupport@spectragenetics.com and we w...
Read MoreLicensing
...SpectraGenetics standard user licenses are shown here. Reporter-tagged Full Length Genes FAP-tagged Genes To obtain additional use or commercial rights to any of our products please send an email to sales@spectragenetics.com...
Read MoreOrders
...tation form below. (If you wish to discuss your request prior to or during completion of the RFQ, you are encouraged to contact us at 1.412.488.9350.) 2. Complete Tagged Gene Order Form below upon receipt of Quotation Alternatively, you may complete the physical forms from the links beneath and either email them to admin@spectragenetics.com or fax them to 1.412.488.9355. Request for Quote Form Tagged Gene Order Form Request for Quotation Form Requ...
Read MoreContact
... We are located at 2403 Sidney Street, Pittsburgh, PA 15203 Phone: 412 488-9350 email: info@spectragenetics.com Please contact us by phone or email for more information about our products or to discuss your specific assay needs. ...
Read MoreServices
...n also screen compounds on our validated GPCR expressing cell lines. Contact us to discuss. To discuss the construction of a new GPCR, cell line or for screening compounds, please send an email to sales@spectragenetics.com and we will get back to you shortly....
Read MoreValidated GPCR Cell Lines for Drug Discovery
...SpectraGenetics has validated more than 100 cell lines expressing N-terminal FAP-tags. Cell Lines are ready for drug screening. Pricing: $7,950 per cell line Please contact sales@spectragenetics.com for further information. AVAILABLE CELL LINES ...
Read MoreVectors Expressing Human GPCRs
...Vectors that express human GPCRs with N-terminal FAP tags. SpectraGenetics offers a variety of vectors (pMFAP2, pBabe-FAP and pSH-FAP) for hundreds of human GPCRs. Pricing: $1,700 each Please contact sales@spectragenetics.com for further information AVAILABLE VECTORS ...
Read MoreTechnology
...applications can be viewed here. Please contact us at info@spectragenetics.com for more information about these assays, or to discuss your specific assay needs. Properties of our standard FAPs and fluorogens are summarized below A chart of our standard FAPs and fluorogens is shown below. FAP tags were developed at Carnegie Mellon University over the past decade and a half and are the subject of multiple patents including US8664364, US9023998, US92...
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