SpectraGenetics has validated more than 30 cell lines expressing FAP-tagged GPCRs accross 3 assay formats; 1-color internalization, 2-color internalization and 2-color/2 target Multi-plex.
2-Color Pulse/Chase Internalization and Trafficking (Original Publication):
ADRB2 ADRA1D ADORA2A
CXCR4 ADRA2A DRD2
SSTR2 ADRA2B GPR120
OPRM1 ADRA2C GCGR
ADRA1A ADRB1 GIPR
ADRA1B CCR5
1-Color Internalization (Original Publication):
ADRA1A ADRB1 CX3CR1 PSGR
ADRA1B ADRB2 CXCR1
ADRA1D ADRB3 CXCR4
ADRA2A BDKRB1 FPR2
ADRA2B BDKRB2 HTR2A
ADRA2C CCR5 OPRM1
2-Target Multi-Plex (Original Publication):
ADRB2/CCR5
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